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Product Center

Intermediates and Apis

Pregabalin
Product Name	CAS NO.	Structure	Specification	Production Scale
3-isobutylglutaric acid	75143-89-4		Off-white to white crystalline solid Purity≥99%	Commercial Scale
3-Isobutyl glutarimide/4-Isobutylpiperidine-2,6-dione	916982-10-0		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
3-isobutylglutaric anhydride	185815-59-2		Brownish red liquid Purity≥98% Toluene≤2.0% Acetic acid≤0.8%	Commercial Scale
3-Carbamoymethyl-5-methylhexanoic acid	181289-15-6		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid	181289-33-8		White crystalline solid Purity≥99% Any single impurity≤0.5% ee≥99.5%	Commercial Scale
Ethyl 2-Carboxyethyl-3-Cyano-5-Methylhexanote	186038-82-4		Colorless to light yellow liquid Purity≥90% Unknown single impurity≤1.0%	Commercial Scale
(S)-3-Cyano-5-methyl hexanoic acid ethyl ester	181289-39-4		Light yellow to colorless transparent liquid Purity≥99% Any single impurity≤0.3% ee≥99%	Pilot scale

Lurasidone
Product Name	CAS NO.	Structure	Specification	Production Scale
Trans-1,2-Cyclohexanedicarboxylic acid	2305-32-0		Light yellow to off-white powder Purity≥98%	Commercial Scale
(1R,2R)-1,2-Cyclohexanedicarboxylic acid	46022-05-3		Off-white to white crystalline solid Purity≥98% Any single impurity≤1.0% ee≥99%	Commercial Scale
(1R,2R)-1,2-Cyclohexanedimethanol	65376-05-8		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5% ee≥99.5%	Commercial Scale

Bicalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
4-Amino-2-(trifluoromethyl)benzonitrile	654-70-6		Off-white to white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide	90357-53-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide	90357-51-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide	90356-78-8		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Enzalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
4-Isothiocyanato-2-(trifluoromethyl)benzonitrile	143782-23-4		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
Enzalutamide	915087-33-1		Off-white to white crystalline solid Purity≥99%	Pilot Scale
4-Bromo-2-fluoro-N-methylbenzamide	749927-69-3		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine	1289942-66-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester	1332524-01-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale
Methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate	1802242-47-2		Off-white to white crystalline powder Purity≥99% Any single impurity≤0.3%	Commercial Scale
Methyl 4-bromo-2-fluorobenzoate	179232-29-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Apalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
Methyl 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylate	2227589-23-1		Off-white to white crystalline solid Purity≥99%	Laboratory Scale
5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile	573762-62-6		Light brown to off-white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
4-((1-cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide	915087-26-2		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Pilot Scale
1-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylic acid	2170654-26-7/ 2227589-22-0		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Laboratory Scale
Cyclobutanecarboxylic acid	3721-95-7		Off-white to white crystalline solid Purity≥98% Any single impurity≤0.5%	Laboratory Scale
1-bromocyclobutanecarboxylic acid	32122-23-9		Off-white to white crystalline solid Purity≥98% Any single impurity≤0.5%	Laboratory Scale
Diethyl 1,1-cyclobutanedicarboxylate	3779-29-1		Light yellow to colorless transparent liquid Purity≥98% Any single impurity≤1.0%	Laboratory Scale
1,1-Cyclobutanedicarboxylic acid	5445-51-2		Off-white to white crystalline solid Purity≥98% Any single impurity≤1.0%	Laboratory Scale
Methyl 4-Amino-2-Fluorobenzoate	73792-08-2		Orange to brown solid Purity≥98% Any single impurity≤0.5%	Laboratory Scale
Methyl 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)cyclobutane-1-carboxylate	2227589-23-1		Off-white to white crystalline solid Purity≥99%	Laboratory Scale

Darolutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
5-Acetyl-1H-Pyrazole-3-carboxylic acid	1297537-45-1		Light yellow to off-white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale
2-Chloro-4-(1H-pyazol-3-yl)benzonitrile	1297537-37-1		Off-white to white powder Purity≥99% Any single impurity≤0.2%	Commercial Scale

Proxalutamide
Product Name	CAS NO.	Structure	Specification	Production Scale
4-amino-3-fluoro-2-(trifluoromethyl)benzonitrile	1095188-12-7		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Ensitrelvir
Product Name	CAS NO.	Structure	Specification	Production Scale
3-tert-butyl-6-(ethylthio)-1,3,5-triazine-2,4(1H,3H)-dione	1360105-53-8		Off-white to white powder Purity≥98%	Laboratory Scale
6-(ethylthio)-1-(2,4,5-trifluorobenzyl)-1,3,5-triazine-2,4(1H,3H)-dione	2771355-74-7		Off-white to white powder Purity≥98%	Laboratory Scale

Midazolam
Product Name	CAS NO.	Structure	Specification	Production Scale
2-Amino-5-chloro-2'-fluorobenzophenone	784-38-3		Yellow needle shaped crystalline solid Purity≥99.5% Any single impurity≤0.2%	Commercial Scale
7-Chloro-5-(2-fluoro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one	2886-65-9		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Laboratory Scale

Tolvaptan
Product Name	CAS NO.	Structure	Specification	Production Scale
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one	160129-45-3		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one	137982-91-3		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one	137977-97-0		Light yellow to off-white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
2-Methyl-4-(2-methylbenzoylamino)benzoic acid	317374-08-6		Off-white to white powder Purity≥99% Any single impurity≤0.5%	Commercial Scale

Mirogabalin
Product Name	CAS NO.	Structure	Specification	Production Scale
3-Ethylbicyclo[3.2.0]hept-3-en-6-one	1235479-59-0		Light yellow to colorless transparent liquid Purity≥98% Any single impurity≤0.5%	Commercial Scale

Conivaptan
Product Name	CAS NO.	Structure	Specification	Production Scale
1,2,3,4-Tetrahydro-benzo[b]azepin-5-one	1127-74-8		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale
4-[(Biphenyl-2-ylcarbonyl)amino]benzoic acid	168626-74-2		Off-white to white solid Purity≥98% Any single impurity≤0.5%	Pilot Scale

Brivaracetam
Product Name	CAS NO.	Structure	Specification	Production Scale
3-propylpentanedioic acid	4165-98-4		Off-white to white crystalline solid Purity≥99% Any single impurity≤0.5%	Commercial Scale

Torezolid
Product Name	CAS NO.	Structure	Specification	Production Scale
3-Fluoro-4-broMoaniline	656-65-5		Off-white to white crystalline solid Purity≥99%	Laboratory Scale

Drotaverin
Product Name	CAS NO.	Structure	Specification	Production Scale
3,4-Diethoxyphenylacetonitrile	27472-21-5		Off white to white powder Purity≥98% Any single impurity≤1.0%	Laboratory Scale

Others
Product Name	CAS NO.	Structure	Specification	Production Scale
2-trifluoromethyl-4-amino benzoic acid	393-06-6		Light yellow to yellow crystal solid Melting point: 183-186℃ Purity≥98%	Laboratory Scale
3,5-Difluorobenzonitrile	64248-63-1		Off white to white powder Purity≥99% Any single impurity≤1.0%	Laboratory Scale

Lorazepam
Product Name	CAS NO.	Structure	Specification	Production Scale
2-Amino-2',5-dichlorobenzophenone	2958-36-3		Light yellow to yellow crystalline solid Purity≥99% Any single impurity≤0.2%	Commercial Scale

Finerenone
Product Name	CAS NO.	Structure	Specification	Production Scale
Benzyl Acetoacetate	5396-89-4		Light yellow to brownish yellow liquid Purity≥96.0% Any single impurity≤2.0%	Commercial Scale

Osimertinib
Product Name	CAS NO.	Structure	Specification	Production Scale
4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9		Light yellow to brown solid Purity≥99% Any single impurity≤0.5%	Pilot Scale

Nafamostat Mesylate
Product Name	CAS NO.	Structure	Specification	Production Scale
6-Cyano-2-naphthol	52927-22-7		Off- white to light brown solid Purity≥99% Any single impurity≤0.5%	Pilot Scale

Upadacitinib
Product Name	CAS NO.	Structure	Specification	Production Scale
2-Bromo-5H-pyrrolo[2,3-b]pyrazine	875781-43-4		Light yellow to yellow-brown solid Purity≥98% Any single impurity≤1.0%	Laboratory Scale
N-Tosyl-5-bromo-4,7-diazaindole	1201186-54-0		Light yellow to yellow-brown solid Purity≥98% Any single impurity≤1.0%	Laboratory Scale
Carbamic acid,N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]-, ethyl este	1869118-24-0		Off white to white powder Purity≥99% Any single impurity≤0.5%	Laboratory Scale

Evocalcet
Product Name	CAS NO.	Structure	Specification	Production Scale
tert-butyl 2-(4-bromophenyl)acetate	33155-58-7		Light yellow to colorless transparent liquid Purity≥98% Any single impurity≤1.0%	Laboratory Scale

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